Caffeine, Chocolate and Harm

Código SC1-E7001-I

VIEW:78 DATA:2020-03-20

Caffeine - Theobromine - Theophylline

Caffeine is 1,3,7-trimethylxanthine - a very bitter white crystalline powder. In medicine, caffeine is used as a cardiac stimulant and a diuretic. It also produces an energy boost, or an increase in alertness - so drivers and students drink liters and coffee to stay awake.

Caffeine - Theobromine - Theophylline

Caffeine is 1,3,7-trimethylxanthine - a very bitter white crystalline powder. In medicine, caffeine is used as a cardiac stimulant and a diuretic. It also produces an energy boost, or an increase in alertness - so drivers and students drink liters and coffee to stay awake. Caffeine is an addictive drug - physical and psychological. It operates by mechanisms similar to amphetamines and cocaine . Its effects, however, are weaker than these drugs, but it acts on the same receptors in the central nervous system (CNS).
If you feel like "it doesn't work" without a cup of coffee, it's because you're already addicted to caffeine ...

The binding of adenosine, a natural neurotransmitter , to its receptors, decreases neural activity, dilates blood vessels, among others. Caffeine binds to adenosine receptors and prevents its action on the CNS. Caffeine stimulates neural activity and causes blood vessels to constrict , as it blocks the action of adenosine. Many headache medications, such as Aspirin Forte, contain caffeine - if you are suffering from a vascular headache, caffeine will constrict blood vessels and relieve pain. With increased neural activity , the pituitary gland (located over the kidneys) "thinks" that some kind of emergency is taking place, andreleases large amounts of adrenaline , which causes a series of effects on the human body, such as tachycardia , increased blood pressure , opening of the respiratory tubes (so many asthma drugs contain caffeine), increased metabolism and muscle contraction, among others.

Another mode of action of caffeine is the blocking of the enzyme phosphodiesterase , responsible for the breakdown of the messenger cAMP, so the excitatory signals of adrenaline persist for much longer. Notice how the structures of caffeine, adenosine and cAMP are similar .
Caffeine also increases the concentration of dopamine in the blood (as do amphetamines and cocaine), by decreasing its reuptake in the CNS. Dopamine is also a neurotransmitter (related to pleasure) and it is suspected that it is precisely this increase in dopamine levels that leads to caffeine addiction.
summing up, caffeine, in the short term, prevents you from sleeping because it blocks the reception of adenosine; it gives you more "energy" as it causes the release of adrenaline, and makes you feel better, as it manipulates dopamine production.

The problem of caffeine consumption only appears in the long run. Most important is the effect that caffeine has on sleep. Reception of adenosine is very important for sleep, especially for deep sleep. The half-life of caffeine in the body is 6 hours . So, if you drink a cup of coffee (200 mg of caffeine) at around 15:00, about 100 mg of caffeine will still be in your body by 21:00. You will still be able to sleep, but you probably will not enjoy the benefits of deep sleep.The next day, you'll need more caffeine to feel better, and this vicious cycle continues, day after day. If you try to stop consuming caffeine, you will feel depressed and, at times, with a terrible headache - caused by excessive dilation of blood vessels in the brain. These negative effects force you to rush back to caffeine consumption. This is the main reason that soft drink manufacturers add caffeine to their products - the consumer becomes addicted and sales increase!

Studies indicate that caffeine consumption during pregnancy can be harmful to the fetus, but scientists guarantee that the problems only appear if the consumption is exaggerated. Caffeine can be lethal if taken in large quantities. The dose required to kill 50% of a certain group of individuals ( LD-50 ) is 75mg / kg. For an adult of about 80 kg, it would be necessary to have the equivalent of something like 150 cups of coffee.
 

dimethylxanthine (theophylline) -Theophylline - (Theophylline.mol)

ChemSpider ID:2068
Empirical Formula:7 H 8 N 4 O 2
Molecular Weight:180,164
Nominal Mass:180 Da
Average Mass:180,164 Da
Monoisotopic Mass:180.064726 Da
Systematic Name1,3-dimethyl-7H-purine-2,6-dione
SMILES:O = C2N (c1ncnc1C (= O) N2C) C

trimethylxanthine (caffeine), Caffeine (Caffeine.mol)

ChemSpider ID:2424
Empirical Formula:C8H10N4O2
Molecular Weight:194,1906
Nominal Mass:194 Da
Average Mass:194,1906 Da
Monoisotopic Mass:194.080376 Da
Systematic Name1,3,7-trimethylpurine-2,6-dione
SMILES:O = C2N (c1ncn (c1C (= O) N2C) C) C

dimethylxanthine (theobromine). Theobromine (Theobromine.pdb)

ChemSpider ID:5236
Empirical Formula:7 H 8 N 4 O 2
Molecular Weight:180,164
Nominal Mass:180 Da
Average Mass:180,164 Da
Monoisotopic Mass:180.064726 Da
Systematic Name3,7-dimethylpurine-2,6-dione
SMILES:O = C2N (c1ncn (c1C (= O) N2) C) C

Caffeine and Similars

What's in common between coffee, coca cola, soft drinks in general and chocolate?

One of the substances that are in common in these products is caffeine and its similar, which are alkaloids.

And what is an alkaloid?

Alkali are substances produced by plants usually produce dependence factors, changes in hormonal and nervous system is placed at the end of phosphine in alkaloids such as caffeine, nicotine, cocaine, heroin, morphine.

What is caffeine? .

Caffeine is the popular name for an alkaloid in the xanthine family, the most important of which are 1,3,7, trimethylxanthine which is caffeine and is most present in coffee, another is 1,3, dimethylxanthine which is the most theophylline. present in tea, and 3.7, dimethylxanthine which is the theobromine most present in chocolate. Caffeine in the human body turns into both theophylline and theobromine.

Caffeine and its products are classified as drugs that act on the hormonal and nervous system.

In a nutshell, what's wrong with caffeine?

Like most drugs, caffeine is addictive, that is, the person becomes addicted, which is why caffeine is added to soft drinks, as this way more soda is sold, and in addition it causes hormonal and nervous changes.

But do these products harm living in society?

Products containing xanthines alter the nervous system, amplifying, on average, irritation and impatience, favoring stress and depression and thus impairing society.

The xanthines, among them caffeine, increase the concentration of adrenaline, such hormone is directly linked to the feeling of danger and irritation. In society, more is needed for peace, patience, self-control and such factors are not caused by xanthines such as caffeine, which generate a pleasure effect, with the side effect of increasing irritability.

Do these products interfere with the spiritual factor?

If a person believes the Bible. and reads the following text:

1Co 3:16 Do you not know that you are a sanctuary of God, and that the Spirit of God dwells in you?
1Co 3:17 If anyone destroys the sanctuary of God, God will destroy him; for the sanctuary of God, which is you, is sacred.
Soon God will destroy everyone who destroys the sanctuary of God that is our body.




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Tags

health, caffeine, theobromine, alkaloid, coffee, chocolate, addiction