Carcinogenic agents table

Agents Classified by the IARC Monographs, Volumes 1—122

CAS No.

Agent

Group

Volume

Year

Additional information

High-temperature frying (see Frying)

Household combustion of biomass fuel (see Biomass fuel, indoor emissions from household combustion of)

Household combustion of coal (see Coal, indoor emissions from household combustion)

Human herpesvirus type 4 (see Epstein-Barr virus)

Human herpesvirus type 8 (see Kaposi sarcoma herpesvirus)

Human immunodeficiency virus type 1 (infection with)

1

67, 100B

2012

Human immunodeficiency virus type 2 (infection with)

2B

67

1996

Human papillomavirus genus beta (except types 5 and 8) and genus gamma

3

90, 100B

2012

Human papillomavirus type 68

2A

100B

2012

Human papillomavirus types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59

1

64, 90, 100B

2012

NB: The HPV types that have been classified as carcinogenic to humans can differ by an order of magnitude in risk for cervical cancer

Human papillomavirus types 26, 53, 66, 67, 70, 73, 82

2B

100B

2012

Human papillomavirus types 30, 34, 69, 85, 97

2B

100B

2012

NB: Classified by phylogenetic analogy to the HPV genus alpha types classified in Group 1

Human papillomavirus types 5 and 8 (in patients with epidermodysplasia verruciformis)

2B

100B

2012

Human papillomavirus types 6 and 11

3

90, 100B

2012

Human T-cell lymphotropic virus type I

1

67, 100B

2012

Human T-cell lymphotropic virus type II

3

67

1996

Hypochlorite salts

3

52

1991

Implanted foreign bodies of metallic chromium or titanium and of cobalt-based, chromium-based, and titanium-based alloys, stainless steel and depleted uranium

3

74

1999

Implanted foreign bodies of metallic cobalt, metallic nickel and an alloy powder containing 66-67% nickel, 13-16% chromium, and 7% iron

2B

74

1999

Insulation glass wool

3

43, 81

2002

Involuntary smoking (see Tobacco smoke, second-hand)

Ionizing radiation (all types)

1

100D

2012

Iron and steel founding (occupational exposure during)

1

34, Sup 7, 100F

2012

Isopropyl alcohol manufacture using strong acids

1

Sup 7, 100F

2012

Isopropyl oils

3

15, Sup 7, 71

1999

JC polyomavirus (JCV)

2B

104

2014

Jet fuel

3

45

1989

Kaposi sarcoma herpesvirus

1

70, 100B

2012

Lead compounds, inorganic

2A

Sup 7, 87

2006

Lead compounds, organic

3

23, Sup 7, 87

2006

NB: Organic lead compounds are metabolized at least in part, to ionic lead both in humans and animals. To the extent that ionic lead, generated from organic lead, is present in the body, it will be expected to exert the toxicities associated with inorganic lead

Leather dust

1

100C

2012

Leather goods manufacture

3

25, Sup 7

1987

Leather tanning and processing

3

25, Sup 7

1987

Lumber and sawmill industries (including logging)

3

25, Sup 7

1987

Madder root (Rubia tinctorum)

3

82

2002

Magenta production

1

Sup 7, 57, 99, 100F

2012

Magnetic fields, extremely low-frequency

2B

80

2002

Magnetic fields, static

3

80

2002

Malaria (caused by infection with Plasmodium falciparum in holoendemic areas)

2A

104

2014

Mate, not very hot (drinking)

3

51, 116

2018 online

Mate, hot (see Very hot beverages)

Merkel cell polyomavirus (MCV)

2A

104

2014

Metabisulfites

3

54

1992

Metallic implants prepared as thin smooth films

2B

74

1999

Methylmercury compounds

2B

58

1993

NB: Evaluated as a group

Microcystis extracts

3

94

2010

Mineral oils, highly-refined

3

33, Sup 7

1987

Mineral oils, untreated or mildly treated

1

33, Sup 7, 100F

2012

Modacrylic fibres

3

19, Sup 7

1987

MOPP and other combined chemotherapy including alkylating agents

1

Sup 7, 100A

2012

Neutron radiation

1

75, 100D

2012

NB: Overall evaluation upgraded to Group 1 with supporting evidence from other relevant data

Nickel compounds

1

Sup 7, 49, 100C

2012

Nickel refining (see Nickel compounds)

11

1976

Nitrate or nitrite (ingested) under conditions that result in endogenous nitrosation

2A

94

2010

Non-arsenical insecticides (occupational exposures in spraying and application of)

2A

53

1991

Oestrogen (see Estrogen)

Opisthorchis felineus (infection with)

3

61

1994

Opisthorchis viverrini (infection with)

1

61, 100B

2012

Oral contraceptives, combined estrogen-progestogen (see Estrogen-progestogen oral contraceptives)

Organic polymeric materials

3

74

1999

Orthopaedic implants of complex composition and cardiac pacemakers

3

74

1999